- Execute sophisticated experiments using advanced computational techniques on Linux-based computer workstations to drive the discovery of new medicines
- Serve as a scientific expert in multi-disciplinary discovery project teams that include chemists, structural biologists, and other discovery scientists, by providing key expertise in the use and interpretation of structural data related to drug targets and their ligands/inhibitors.
- Clearly communicate the results of computational experiments and interpretations of structure to project team members.
- Develop novel computational methods and/or workflows to address key drug discovery questions.
- Collaborate with other computational scientists to incorporate new computational technologies in a project team setting (e.g., Artificial Intelligence, Machine Learning).
- A PhD in Computational Chemistry (or to be completed before the time of hire) or related discipline is required, OR a Masters degree in Chemistry or related field with at least 12 years of drug discovery industry experience is required OR a Bachelors degree in Chemistry or related field with at least 14 years of drug discovery industry experience is required
- Post-doctoral experience is highly preferred.
- A strong scientific track record of publications in peer-reviewed journals and/or patent literature is required.
- Excellent written and verbal communication skills are required.
- Experience in the application of computational chemistry tools and methodologies to the drug discovery process is preferred (examples may include: docking, high-throughput virtual screening, AI/ML, cheminformatics, molecular dynamics, quantum mechanics, homology modeling, etc.).
- Ability to script workflows and implement new algorithms to analyze large-scale data sets from multiple sources is preferred
- Experience working with multi-disciplinary/cross functional teams is preferred
- Familiarity with one or more commercial computational chemistry packages is preferred (examples might include: Maestro/Schrodinger, MOE/Chemical Computing Group, OpenEye, Pipeline Pilot)
- This position is located in Spring House, PA, or La Jolla, CA, and may require up to 10% travel.
United States-Pennsylvania-Spring House-
United States-California-La Jolla, United States-California-San Diego
Janssen Research & Development, LLC (6084)